DSIP

CAS #: 62568-57-4

Molecular Formula: C₃₅H₄₈N₁₀O₁₅

Molecular Weight: approx. 848.81 g/mol

DSIP (Delta Sleep–Inducing Peptide) is a naturally occurring neuropeptide first isolated from the hypothalamus and studied for its role in sleep regulation, stress modulation, and neuroendocrine balance. It is a small peptide composed of nine amino acids and has been investigated for its potential effects on sleep architecture, circadian rhythm regulation, and hormonal modulation.

Sleep Architecture Support: Originally identified for its ability to promote delta-wave (deep) sleep, potentially enhancing restorative sleep cycles.

Stress & Cortisol Modulation: May influence the hypothalamic–pituitary–adrenal (HPA) axis, supporting improved stress resilience and cortisol regulation.

Neurotransmitter Regulation: Demonstrates potential interactions with GABA, serotonin, and other central nervous system signaling pathways.

Hormonal Influence: Some research suggests modulation of growth hormone and luteinizing hormone release, though effects appear variable.

Neuroprotective Properties: Investigational models indicate potential benefits in protecting against oxidative stress and supporting neural recovery.

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